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Depression & moodFor practitioners110 min read

Treating depression in adults: a therapist's manual

A protocol of sixteen sessions, session by session, built on cognitive behavioural therapy for depression and on behavioural activation. Assessment and diagnostic sorting first — including screening for bipolarity and assessment of suicide risk —, then formulation, activation, the obstacles to activation, rumination, work on thoughts, behavioural experiments, problem solving, sleep, relationships, rules and self-criticism. The place of medication stated plainly, detailed conduct of activation, safety planning, relapse prevention, worksheets to hand the patient, and full references.

In short

This manual is written for mental health professionals trained in cognitive behavioural therapy with adults. It describes complete management of a major depressive episode: the presentations that must be ruled out — first among them bipolar disorder, whose misrecognition has direct treatment consequences —, the assessment of suicide risk and the safety plan, the behavioural and cognitive model that explains how the episode is maintained, the DSM-5-TR and ICD-11 criteria, then the sixteen sessions one by one, with their step-by-step run-through, what to say, what never to say, and the criterion for moving on. Behavioural activation occupies the first half of the protocol because it is what acts fastest and what a severely slowed patient can actually do. The place of medication is stated plainly, without campaigning in either direction. And relapse prevention is not left to the final session: in a recurrent disorder, it is the object of treatment. Seven printable worksheets accompany the programme.

Topic
Depression & mood · Emotions
Who it's for
For practitioners
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The programme

This programme is a treatment manual intended for mental health professionals. It presupposes clinical training, experience of working with adults, and a supervision framework. It replaces neither your clinical judgement nor your ethical responsibility. The diagnostic criteria are reformulated in our own words, never reproduced: refer to the original manuals for the letter of the text.

1. The programme at a glance

Indication. A major depressive episode in an adult, mild to severe, single or recurrent, with or without concurrent medication.

Reference model. Beck and colleagues' cognitive therapy of depression, and behavioural activation in the form systematised by Martell, Dimidjian and Herman-Dunn. The protocol follows the order the data support: behavioural first, cognitive next, beliefs last.

Format. Sixteen individual sessions of 50 minutes: weekly until session 10, then fortnightly. Two booster sessions, at one month and at three months.

Target mechanism. Not to lift mood directly, but four changes: to restart behaviours that produce reinforcement, to interrupt rumination, to undo the interpretations that maintain withdrawal, and to make the patient able to recognise and stop the next episode.

Session Focus Session output
1 Assess, measure, set the frame Record installed, risk assessed
2 The formulation, and the model Written formulation of the case
3 Activation: observing One week of activities recorded
4 Activation: scheduling Three activities planned
5 The obstacles to activation Analysis of one failed schedule
6 Rumination Signal and postponement installed
7 Spotting thoughts Three-column record
8 Putting thoughts to the test Five-column record
9 Behavioural experiments One prediction tested
10 Problem solving One problem worked in six steps
11 Sleep, the body, substances Fixed rising time
12 Relationships, and what has gone out Two contacts resumed
13 Rules and beliefs One rule identified and loosened
14 Self-criticism Written answer to the critical voice
15 Consolidating Relapse sheet begun
16 Review and relapse prevention Written plan in the patient's hand

What the patient takes away. Seven printable worksheets, listed in section 36 and downloadable from this page: my record, my days, my thoughts, my experiments, my safety plan, my rumination, my relapse plan.

What sets this programme apart from supportive work. Supportive work accompanies the episode. This programme does three things more: it restarts behaviours before the wish to act returns, it treats rumination as a behaviour rather than as a thought, and it explicitly prepares for the next episode — because there will probably be one.

2. Before you begin

Who this programme is for

This text is written for psychologists, psychiatrists, psychotherapists and doctors trained in cognitive behavioural therapy with adults. It assumes you can conduct a diagnostic interview, that you can assess suicide risk and act on it, and that you can work with a prescriber.

It is not written for patients. It contains procedures, thresholds and criteria for non-response, and it raises matters — suicide, medication, prognosis, non-response — that must be put differently when you are speaking to the person concerned.

The question that comes first: which depression is this?

Three decisions are taken before the first procedure, and they are not taken in one session.

Is this a major depressive episode? A fortnight of low spirits after a break-up is not one. Section 5 gives the elements, section 7 gives what must be ruled out.

Has there been a hypomanic or manic period? This is the most important question in the whole manual, and it is asked of every depressed patient, without exception. A bipolar disorder treated as unipolar depression exposes the patient to a switch, and the diagnosis is missed in a substantial proportion of cases because nobody asks. See section 7.

What is the suicide risk, now? Section 10 is devoted entirely to it, and it is not optional.

What this programme does not treat

It does not treat a grief that is running its course. The distinction is developed in section 7; it is delicate, and it is not settled by duration alone.

It does not treat bipolar depression. Behavioural and cognitive work has its place there, but within a different framework, with a mood stabiliser and close attention to the sleep-wake rhythm.

It does not, on its own, treat a severe depression with psychotic features, major retardation, or malnutrition. These are situations where psychiatric opinion comes first, and sometimes admission.

It does not replace medical assessment. A physical work-up is part of the assessment, and the question of medication belongs to a doctor.

What this programme is not

It is not drug treatment, and it is not a substitute for it. The place of medication is stated in section 12, plainly and without evasion.

It is not a therapy of causes. History matters and it is taken up in session 2, but the episode is treated through what maintains it today, not through what triggered it twenty years ago.

It is not a programme of positive thinking. Dark thoughts are not replaced with pleasant ones: they are put to the test of the facts, and it sometimes turns out that they are true — in which case one moves to problem solving.

How to use it

Read the whole manual before the first session, in particular sections 7, 10, 12 and 32: the differential, suicide risk, medication, and the conduct of activation. These are the four places where things go wrong.

Each session is described on the same frame: the aim, the run-through in steps, what you say, the common errors, and the criterion for moving on.

One warning particular to this disorder. Your patient will arrive saying that this is pointless, that he has not done the exercises, and that you are wasting your time. This is not a refusal of care: it is the symptom speaking. How you receive that sentence in session 3 often decides the rest of the treatment.

3. The clinical picture

What patients describe

They rarely describe sadness first. They describe an extinction: no more desire, no more taste for anything, no more impetus, and a fatigue that rest does not repair.

The phrases that recur: "I don't feel like anything", "I have to force myself for everything", "I don't recognise myself", "I'm a burden to the people around me", and "I can't see how this could ever get better". That last one is at once a symptom, a treatment target, and an element of suicide risk.

They also describe an inversion of the usual order: they are waiting to feel like it before doing it. That is exactly the opposite of what treatment asks, and the sentence is worth writing down verbatim in session 1 — it will be used in session 4.

The three groups of symptoms

Mood and anhedonia. Sadness, but above all loss of interest and pleasure. Anhedonia is often more informative than sadness: many patients do not say they are sad, they say they are empty, switched off, or they say nothing at all.

The somatic side. Sleep — initial insomnia, early waking, or hypersomnia —, appetite, weight, energy, retardation or agitation, reduced libido, pain.

The cognitive side. Concentration, indecision, slowed thinking, self-deprecation, guilt, pessimism, thoughts of death. Complaints of poor memory are frequent and are a symptom of the depression, not a sign of dementia — an important point in older adults.

What maintains the episode

This is the useful part of the picture, because it is the part one treats.

Withdrawal. Less activity, so fewer opportunities for reinforcement, so less desire, so less activity. This loop is the protocol's main target.

Avoidance. Not laziness: a flight from what has become costly — people, work, tasks, and sometimes the bed itself becomes a refuge.

Rumination. Hours spent on "why is this happening to me", "what is wrong with me". It gives the feeling of looking for a solution and it worsens mood measurably.

Interpretations. A negative reading of self, others and the future; internal, global and stable attribution of failures; disqualification of anything that goes well.

Real consequences. Sick leave, conflict, debt, isolation — which in turn feed the episode. Section 24 deals with this point: some dark thoughts are accurate, and what is accurate is solved rather than restructured.

What depression is not

It is not sadness. Sadness is a normal emotion, directed at an object, that varies with circumstances. Depression is a lasting state that extinguishes responsiveness itself.

It is not a lack of willpower. This is the most important sentence in the feedback, and it can be demonstrated: will is precisely one of the functions the disorder impairs.

It is not a flaw of character, and it is not a strength of character to be admired either. Both discourses do harm.

It is not always a signal. Some episodes have an obvious biographical meaning, others arise in a life that is going well. Insisting on finding a cause in the latter produces guilt and nothing else.

Epidemiology, in four useful figures

Depression is one of the commonest mental disorders, with a lifetime prevalence of the order of fifteen to twenty per cent, and a yearly prevalence around five per cent.

It is about twice as common in women, with a gap that appears in adolescence.

It is recurrent: after a first episode the risk of another is high, and it rises with the number of previous episodes. This is the central argument for relapse prevention work.

And a substantial proportion of episodes are neither diagnosed nor treated, particularly in men, in older adults, and when the complaint presents in somatic form.

4. The model that guides this programme

Two complementary models, to be explained to the patient

This is the most profitable explanation in the programme, and it takes twenty minutes in session 2, with a sheet of paper.

The behavioural model. An event, a loss, exhaustion reduce activity. Reduced activity removes the sources of reinforcement — pleasure, accomplishment, contact. Lost reinforcement further reduces desire and activity. Depression is not only caused by what happened: it is maintained by what the person has stopped doing.

The practical consequence is counter-intuitive and must be said in so many words: action comes before the wish to act. One does not wait to feel like it in order to act; one acts, and the wish returns afterwards, partly and slowly.

The cognitive model. Within the episode, interpretation is distorted in three directions: about oneself, about the world, about the future. These interpretations are not lies the patient tells himself: they are plausible readings, produced by a system that filters. They are treated by putting them to the test, not by contradicting them.

What these two models imply

They give the programme's four principles, to be written down with the patient.

We start with behaviour. Because it acts faster, because it is feasible when one can no longer think, and because a patient who has obtained a concrete result becomes capable of cognitive work.

We act before feeling like it. Motivation is not the condition of starting, it is its consequence.

We treat rumination as a behaviour. Not as content to be corrected: as something one does, which has triggers, a duration, and which can be interrupted.

We put thoughts to the test rather than replacing them. Including when they turn out to be true.

What the model explains to the patient

Why he feels worse in the morning. The circadian cycle, and the fact that nothing has yet been done that day.

Why rest does not repair. Because the fatigue of depression is not a sleep debt, and because prolonged rest removes still more reinforcement.

Why he thinks about the same thing endlessly without finding a solution. Because rumination is not problem solving: it is about causes and meanings, not about actions.

Why he judges himself so harshly. Because the filter is in place, and because the same filter prevents him from seeing that it is in place.

Why things are better when he is busy and worse when he is alone at home. That is the behavioural model, observed from the inside.

What the model implies you should not do

Do not wait for desire to return.

Do not aim at sadness first. It moves last. What moves first is the number of activities and the sense of accomplishment.

Do not reassure. "You'll see, it will get better" is probably true and completely inoperative.

Do not argue with negative thoughts head-on. You ask for evidence; you do not supply counter-arguments.

5. The DSM-5-TR criteria, reformulated

The criteria below are a reformulation in our own words, for reference. They do not replace the manual: refer to the DSM-5-TR (American Psychiatric Association, 2022) for the letter of the text and the application notes.

A major depressive episode involves the following.

At least five manifestations present during the same two-week period, representing a change from previous functioning, and among which must figure either a depressed mood or a loss of interest or pleasure.

The manifestations concerned: depressed mood for much of the day, nearly every day; markedly diminished interest or pleasure in almost all activities; significant change in weight or appetite; insomnia or hypersomnia; agitation or retardation observable by others; fatigue or loss of energy; feelings of worthlessness or excessive guilt; difficulty concentrating or indecisiveness; recurrent thoughts of death, suicidal ideation, a plan or an attempt.

Clinically significant distress or impairment of functioning.

No attribution to a substance or a medical condition.

No history of mania or hypomania, which would point to a bipolar disorder.

The specifiers that change management

The DSM-5-TR allows one to specify severity, the presence of psychotic features — which require psychiatric opinion —, of melancholic, atypical or anxious features, peripartum onset, a seasonal pattern, and a single or recurrent episode.

Two of these matter particularly here. Anxious distress is associated with slower response and higher suicide risk. And the recurrent character governs the whole final part of the programme.

The most debated point, and what you need to know about it

The removal, in DSM-5, of the bereavement exclusion was and remains debated. The authors' argument is that grief does not protect against a depressive episode and that the exclusion deprived people of care they needed. The critics' argument is that it exposes normal sorrow to medicalisation.

In practice, do not decide on duration. Look at the form: in grief, the pain comes in waves, it is tied to the person who died, self-esteem is generally preserved, and pleasure remains possible between the waves. In a depressive episode, mood is continuous, anhedonia is global, and self-deprecation is aimed at the person himself. See also the manual devoted to prolonged grief.

What these criteria do not say and what must be assessed

They do not measure rumination, which is nevertheless one of the best predictors of chronicity.

They say nothing about avoidance behaviours, which are the main target of treatment.

They say nothing about available support, nor about the real consequences already installed — debt, sick leave, isolation — which determine whether the programme is feasible at all.


This programme is for practitioners

It is written for mental health professionals and requires credential verification, then a professional subscription.

Frequently asked questions

How long before he feels better? The first changes in behaviour often appear around the fourth or fifth session, mood follows several weeks later. Say so from the start: a patient expecting relief in three weeks will conclude that it has failed.

He says he has not done the exercises. Again. Treat it as the data of the session, not as a failing, and divide the size by three. See sessions 3 and 5.

Should he be sent to a doctor for an antidepressant? In moderate to severe presentations, the combination does better. Propose it without making it an admission of failure, and organise the link. See section 12.

He tells me he is thinking about suicide. What do I do now? You explore following section 10, you treat the modifiable factors, you restrict access to means, and you write a safety plan with him in the session. Not a contract: a plan.

How do I know whether it is bipolar? You look for periods of reduced need for sleep without tiredness, you interview a relative, and where in doubt you ask for an opinion before any antidepressant is started. See section 7.

He is better and wants to stop at session 10. This is common and it is the moment when relapse risk is most poorly judged. Propose keeping the spaced sessions and doing at least the work of sessions 15 and 16, which are the ones that protect.

He has been off work for eight months. The return is prepared early, in stages, with contact maintained and a pre-return meeting. Long leave without scheduled activity makes everything worse. See session 12.

Does this work by video? Yes, the data are favourable for this protocol. Two reservations: assessment of suicide risk requires more care, and you need to know where the patient physically is and who can be reached.

He has already had CBT and it did nothing. Ask precisely what was done. Very often: no activation conducted as in section 32, no work on rumination, or a missed diagnosis. It is not "CBT" that failed.

How many episodes before proposing prevention work? From three onwards, propose it explicitly: that is the threshold at which the relapse prevention data are strongest. See sections 11 and 30.

Printable worksheets

The exercises from this programme, as printable PDFs. Members only.

See the plansThe printable worksheets are included with access.
  1. 01My recordOne line a day, two figures. Nothing more.
  2. 02My daysWe do not wait until you feel like it. We write down a day and a time.
  3. 03My ruminationIt is not a thought to be corrected. It is something one does.
  4. 04My thoughtsWe do not replace them with pleasant thoughts. We put them to the test.
  5. 05My experimentsThe prediction is written beforehand. Otherwise the experiment teaches nothing.
  6. 06My safety planThis is not a promise. It is an arrangement, written in advance.
  7. 07My relapse planThere will probably be other difficult periods. You will not be starting from scratch.

Every worksheet in one file, with a table of contents.

depressionmajor depressive episodebehavioural activationcognitive restructuringruminationsuicide risksafety planrelapse preventionantidepressantprotocolmanualprofessionalsDSM-5ICD-11

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